AN UNBIASED VIEW OF LDN-27219 DRUG MECHANISM OF ACTION

EC dysfunction, characterised by blunted relaxations in response to acetylcholine and lowered NO bioavailability, was located in the aortas of male HAS-2 mice, when it was unaltered in the aortas of feminine HAS-2 mice. Superoxide levels amplified and extracellular superoxide dismutase (ecSOD) expression reduced from the aortas of male and woman HA